Who we are

We are a team of experienced operators and dreamers who are passionate about working with founders at the earliest stage. Collectively, we have invested in over 200 early stage startups. We are proud to have an NPS score of 100 from our founders.

Alex Iskold Is a Founder and a Managing Partner at 2048 Ventures.  Alex is a 4x founder, a software engineer, and an investor in over 150 startups. He writes one of the top startup blogs called Startup Hacks. Alex is a life-long learner and interested in Complexity Science and Systems Thinking.

Prior to founding 2048 ventures, Alex spent 5 years at Techstars as the Managing Director of its NYC program. Alex was also the founder and CEO of Info Lab (acquired by IBM), founder and CEO of GetGlue (backed by USV, RRE, Time Warner), and a Chief Architect of distributed computing startup DataSynapse (acquired by TIBCO).

Alex currently serves as a Coach and a VC in Residence at the Harvard Business School. Alex previously taught an award-winning undergraduate computer science class at NYU.  He holds a B.S. in Math with Honors from Lehigh University and M.S. in Computer Science from NYU.

You can see Alex's connections on Linkedin, and follow him on Twitter @alexiskold.

Read what founders say about working with Alex.

Deep Tech
Digital Health

Neha Khera is a General Partner at 2048 Ventures, and has been an early-stage investor for nearly a decade. Prior to 2048 Ventures, Neha was a Partner at 500 Startups and invested in over 40 startups from around the globe. Neha was also co-founder of 500 Startups Canada, and led the fund’s investments in Applyboard, Mejuri, Fightcamp and Benchsci.

Neha has been immersed in the technology industry throughout her career. She started off as a software developer, and worked in circuitry design and telecommunications before making her way to leading tech innovation at one of Canada’s top banks.

Neha has published numerous research papers, and is an advisor to the Engineering Dean at the University of Waterloo. She is a strong supporter of women in technology, having launched and run Girls in Tech Toronto and a TEDx Women conference for a number of years. Neha obtained an Electrical Engineering degree from the University of Waterloo and an MBA from the Richard Ivey School of Business.

You can see Neha’s investments on AngelList, see her connections on LinkedIn, follow her on Twitter @naykhera, or read more about her journey.

Deep Tech

Zann Ali is a Principal at 2048 Ventures. Prior to 2048 Ventures, Zann was at Putnam Investments, where he worked with the Chief Investment and Operating Officers on investments and special projects. Before Putnam, Zann spent four years at Fidelity Investments, first with the company’s internal strategy team and then with Fidelity Health, a Fidelity-funded insure-tech startup that he helped launch.

Zann holds a B.S. in Statistics & Finance with Honors from Babson College and an MBA from the MIT Sloan School of Management. At MIT, Zann was a pre-seed investor with Dorm Room Fund, where he was fortunate to support and invest in 20+ student-founded startups. He also served on the teaching team for MIT’s Entrepreneurial Finance & Venture Capital course.

You can see Zann's connections on LinkedIn, and follow him on Twitter @thisiszann.


Julie Wolf is a Principal at 2048 Ventures. Prior to 2048 Ventures, Julie was at SOSV's IndieBio New York office, where she was the Chief Science Officer. Before IndieBio, Julie spent five years at the American Society for Microbiology, working with scientists to curate and communicate their discoveries. She was co-founder of Brooklyn Bio, a biotech startup creating improved microbial strains.

Julie holds a Ph.D. in Microbiology, Immunology, and Cancer Biology from the University of Minnesota and did her postdoctoral fellowship at Albert Einstein College of Medicine. She is a huge proponent of bio literacy and has taught principles of molecular biology and synthetic biology to many audiences, including at the community biolab Genspace.

You can see Julie's connections on LinkedIn, and follow her on Twitter @juliemariewolf.

Health Tech
Digital Health

Daniella Cohen is a Senior Associate at 2048 Ventures. Prior to 2048 Ventures, she was a managing partner at Rough Draft Ventures where she invested in student founders across the country.

She was a summer associate at Techstars NYC and joined the portfolio company, The Clear Cut (DTC diamond startup) as their Head of Content while the company grew over 100% year-over-year. She also took time off from college to work on social and emotional learning projects at Facebook as the youngest person at the company.

Daniella holds a B.A. in Neuroscience from Princeton University where she led Princeton Women in Entrepreneurship and continues to serve on the board for the Princeton Prize in Race Relations.

You can see Daniella's connections on LinkedIn, and follow her on Twitter @daniellarcohen.

Deep Tech
Digital Health

Minda Brusse is a Venture Partner at 2048 Ventures and also the Co-founder and Managing Director at First Row Partners in Seattle. As a leader in the Pacific Northwest startup ecosystem, she has been a lead organizer for angel funds and networks with the purpose of expanding participation and increasing investment activity.  

With a lengthy startup career that began in the Bay Area, Minda approaches the investor role with the perspective of a founder and entrepreneur.  Past startup leadership roles involved technology solutions across ecommerce & retail, marketplaces, SaaS solutions, and salesforce effectiveness.  These experiences led to her well-developed sense of founding teams, customers and market strategies.

Minda began her career as a Manager at Accenture’s CRM practice after obtaining a degree in Marketing and Retail Studies from Santa Clara University.  An active community leader in the visual arts and civic efforts, she recently co-founded The $1k Project, a volunteer effort focused on pandemic relief.

You can see her connections on LinkedIn or follow her on Twitter at @mindabrusse.

Rachel Soper Sanders is a Venture Partner at 2048 Ventures and also the CEO and co-founder of Rootine, a precision nutrition startup optimizing health and human performance. She is also the team lead at Apex Optimizers, the first collaborative NFT project focused on real world utility in health, sleep, and performance.

In addition to being a founder, Rachel is an angel investor, health and web3 thought leader, toddler mom, and has been featured across Forbes, Entrepreneur, Thrive Global, Business Insider, and more. She has over 10 years' experience at the intersection of health and technology having started her career in investment banking focused on healthcare with additional experience in product and strategy.

Rachel received a BS from Vanderbilt University and an MBA from Harvard Business School.

You can see her connections on LinkedIn or follow her on Twitter at @rachelssanders.

Colby Mascaro is an Operations Manager at 2048 Ventures. She was first introduced to the world of venture in 2020 and has loved being a part of so many startup journeys. Prior to 2048 Ventures, Colby has served in various operations and administrative roles throughout her career.

Colby is originally from New Hampshire, but currently resides in Virginia. She's also a military spouse and proud mom to three handsome little boys.

Colby holds a B.S. in Psychology from Rollins College in Florida.

You can see her connections on LinkedIn.